Hi, I have been on Paxil for a few years but moved up to 30 mg about 4 or 5 months ago. Since then, it's been much much harder to ejaculate. I know that switching meds can. events, there was no clear relationship between adverse events and the dose of Paxil to which patients were assigned, except for impotence and abnormal ejaculation. Abstract. AIMS OF THIS STUDY: To evaluate the efficacy of chronic and 'on demand' administration of paroxetine hydrochloride in the drug treatment of premature ejaculation. On that dosage of Paxil® he had no difficulty either with erection or with ejaculation. It took him approximately 5 minutes to ejaculate. The premature ejaculation was.