What are the possible side effects of tramadol (Ultram, Ultram ER)? Get emergency medical help if you have any of these signs of an allergic reaction: hives. Tramadol Drug is on NOLA.com. NOLA.com gives people the power to share and connect with thousands of users. View, share and connect on NOLA.com. Ultram (Tramadol Hcl) Drug Information: Uses, Side Effects, Drug Interactions and Warnings at RxListULTRAM (tramadol hydrochloride) tablets is a centrally acting. Best Answer: Don't listen to these other answers. Tramadol is an opioid, but not an opiate, so it will not show on a drug test, nor should it cause a false positive.