Use of acyclovir with bell palsy

The AAN guidelines suggest that the use of acyclovir for the treatment of Bell palsy is only possibly effective and that this agent alone is not effective in facial. two placebo-controlled studies supported the use of valacyclovir (Valtrex) 2 or acyclovir (Zovirax) 3 in combination with prednisolone for the treatment of Bell's palsy. Early treatment with prednisolone or acyclovir in Bell’s palsy. N Engl J Med. 2007 Oct 18;357 recent systematic reviews revealed a lack of evidence to support the use. and that clinical trials on acyclovir are inconclusive and therefore cannot be used to make recommendations regarding its use. (10,11) TABLE Therapies for Bell's palsy.

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